By Anna Tampieri, Simone Sprio
This e-book offers a large and interdisciplinary assessment of the present cutting-edge within the improvement of biomimetic fabrics for tissue regeneration at the foundation of correct and high-impact medical wishes. It in particular emphasizes the regeneration of bone, cartilage, and osteochondral tissues in addition to delicate tissues comparable to nerves, center, and endocrine organs. It brings jointly contributions from fabrics scientists, biologists, and surgeons with globally well-known event within the box of regenerative medicine.
The target of the ebook is to focus on the relevance of biomimetics as an optional procedure for the improvement of latest scaffolds that could direct regenerative cascade by way of chemico-physical and topological nano-cues provided to cells and biologic tissues. rather, the publication refers to rising ideas in synthesis strategies and scaffolds encouraged by way of nature in addition to to novel ways for clever functionalization comparable to using magnetic signaling.
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Extra resources for Bio-inspired regenerative medicine : materials, processes, and clinical applications
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Furthermore, the linkage of growth factors to the ECM protects them from enzymatic cleavage and prevents fast diffusion within the tissue . In addition, growth factor activity may be enhanced by localization within the ECM, allowing interaction with its specific ligands . Conversely, some growth factors (examples) may be inactivated by their adhesion to the ECM and while they can act on their target when released by matrix proteolysis , requiring the action of ECM-degrading enzymes expressed by the cells regulated by growth factors and ECM adhesion domains.
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Bio-inspired regenerative medicine : materials, processes, and clinical applications by Anna Tampieri, Simone Sprio