Ciba Foundation Symposium 106 - Human Cataract Formation by PDF

ISBN-10: 0272797758

ISBN-13: 9780272797754

ISBN-10: 0470720875

ISBN-13: 9780470720875

Content:
Chapter 1 creation (pages 1–2): A. Spector
Chapter 2 class of Human Cataractous swap through the yank Cooperative Cataract study staff strategy (pages 3–24): Leo T. Chylack
Chapter three Epidemiological and different stories within the review of things Contributing to Cataractogenesis (pages 25–47): R. M. Clayton, J. Cuthbert, J. Seth, C. I. Phillips, R. S. Bartholomew and J. Mck. Reid
Chapter four Oxidation and Cataract (pages 48–64): Abraham Spector
Chapter five Metabolism and serve as of Glutathione within the Lens (pages 65–87): Venkatn. Reddy and Frank J. Giblin
Chapter 6 Cataracts and Photochemical harm within the Lens (pages 88–109): Raymond F Borkman
Chapter 7 Diabetic and Galactosaemic Cataracts (pages 110–131): Peter F. Kador and Jin H. Kinoshita
Chapter eight Calcium and the body structure of Cataract (pages 132–162): George Duncan and Tim J. C. Jacob
Chapter nine Cytoskeletal Proteins of the growing old Human Lens (pages 163–176): Harry Maisel
Chapter 10 interplay of Crystallins with the Cytoskeletal–Plasma Membrane complicated of the Bovine Lens (pages 177–190): Hans Bloemendal, Wilfried W. De Jong, Frans C. S. Ramaekers, Alphons J. M. Vermorken, Irene Dunia and E. Lucio Benedetti
Chapter eleven Crystallin Genes: Templates for Lens Transparency (pages 191–207): Joram Piatigorsky, John M. Nickerson, Charles R. King, George Inana, J. Fielding Hejtmancik, James W. Hawkins, Teresa Borras, Toshimichi Shinohara, Graeme Wistow and Barbara Norman
Chapter 12 The Crystallin Gene households (pages 208–217): John G. G. Schoenmakers, Johan T. Den Dunnen, Rob J. M. Moormann, Rosalie Jongbloed, Rob W. Van Leen and Nicolette H. Lubsen
Chapter thirteen The Molecular constructions and Interactions of Bovine and Human ??Crystallins (pages 219–236): Lesley Summers, Christine Slingsby, Helen White, Michael Narebor, David Moss, Linda Miller, Daruka Mahadevan, Peter Lindley, Huub Driessen, Tom Blundell, Johan Den Dunnen, Rob Moormann, Rob Van Leen and John Schoenmakers
Chapter 14 The Molecular foundation of Cataract Formation (pages 237–247): George B. Benedek
Chapter 15 Non?Invasive innovations within the research of Cataract improvement on the Metabolic and Protein Molecular point (pages 248–274): William H. Garner

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Example text

Other risk factors include medical conditions and certain drugs. Although individuals may have several risk factors, controls have significantly fewer than cataract patients of the same age. This difference in the number of risk factors is also age-related, as is the degree of divergence from the normal range in the concentrations of several plasma constituents. 1984 Human cataract formation Pitman, London (Ciba Foundation symposium 106) p 25-47 Cataract is a major cause of blindness in man, with grave personal, social and economic consequences.

The first study of the project, a case-control investigation based in Raipur, has been completed. The findings are striking. The results demonstrate a powerful ‘dose-dependent’relationship between severe diarrhoeal disease and the risk of presenile cataract. The findings suggest that persons exposed to two or more episodes of cholera-like diarrhoeal disease may have 21 times higher risk of developing cataract at a relatively young age, and that about 36% of the cases of cataract may be related to severe diarrhoeal disease.

Hockwin: I agree with Dr Minassian that it is not necessary to follow a control group. g. in terms of age) with respect to the statistic that was applied. On this second evaluation, where you introduce the influence of age on several parameters of the blood chemistry, it is interesting to see the changes with age and the importance of the risk factors at different ages. With respect to single risk factors, you have adequate in vivo classification of lens opacities, but I don’t know whether you analysed the individual types of opacities in relation to the risk factors?

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Ciba Foundation Symposium 106 - Human Cataract Formation


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