By Gerd Burmester
Humboldt Univ., Berlin, Germany. Pocket-sized atlas illustrates the elemental rules of immunology and its scientific functions. gains greater than a hundred thirty colour plates describing uncomplicated ideas, laboratory diagnostics, and medical immunology. For physicians and citizens. Softcover.
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Extra info for Color Atlas of Immunology
B. Immunoglobulin ªSuperfamilyº " 26 Globular domains of similar structure are characteristic of an entire series of molecules of the immune system referred to as an immunoglobulin superfamily. , CD56), and polymeric immunoglobulin receptors (poly-IgR). Poly-IgR is responsible for the passage of IgA and IgM through epithelial cells. The superfamily also includes many other antigens whose function has not yet been characterized. C. Determination of Antigen Specificity by Hypervariable Regions The variable domains of heavy and light chains contain regions with extremely variable amino acid sequences.
IL-1 and TNF-a increase vascular permeability, facilitating migration of cells into tissue.
Target recognition by NK cells Cw1,3,7,8 Bw4 A3, A11 HLA-E C. Inhibitory receptors of C. NK cells NK cell Activation Inhibition Cw2,4,5,6 APO-1 Fas ligand DNAfragmentation NKG2D MICA MICB CD95 Target cell KIR2DL1 KIR2DL2 NKR-P1 Apoptosis 1. Nonsecretory lysis Target cell Formation of pores Granzyme Perforin Degranulation Fundamental Principles CD34 CD34+ CD33CD2+ CD7+ CD5+ CD1+ CytCD3+ " 3 DNAfragmentation Apoptosis +necrosis 2. Secretory lysis Target cell Perforin Granzyme NK cell KIR3DL1 KIR3DL2 CD94 + NKG2A DNA fragmentation Apoptosis + necrosis Antibody against target antigen Fc-receptor 3.
Color Atlas of Immunology by Gerd Burmester