Concise Clinical Immunology for Health Professionals by Mary Keogan, Eleanor M. Wallace, Paula O'Leary PDF

By Mary Keogan, Eleanor M. Wallace, Paula O'Leary

ISBN-10: 0203643348

ISBN-13: 9780203643341

ISBN-10: 0415298296

ISBN-13: 9780415298292

ISBN-10: 041529830X

ISBN-13: 9780415298308

This up to date immunology textbook offers a transparent and straightforward advent to scientific and laboratory immunology for future health execs in education or in perform. It covers: crucial uncomplicated immunology medical immunology laboratory investigations of immunological problems remedies utilized in immunological issues. concentrating on scientific difficulties visible in perform and together with self-assessment questions and case histories to help studying and figuring out, this is often a useful source for all scientific scholars, nurses, nutritionists, pharmacists and physiotherapists.

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Bone marrow Haematopoietic stem cell Megakaryocyte/ erythrocyte progenitor Common myeloid progenitor Common Iymphoid progenitor Granulocyte/macrophage progenitor Megakaryocyte Erythroblast Blood B T Neutrophil Basophil Eosinophil Platelets Erythrocyte B cell T cell NK Monocyte Natural killer cell Precursor Immature dendritic cell Tissue T Plasma cell Activated T cell Macrophage Mast cell Immature dendritic cell Dendritic cell Dendritic cells Dendritic cells are professional APCs, which migrate from blood into tissues.

Naïve lymphocytes recirculate until they meet their cognate antigen. If this does not occur they die. g. dendritic cells) take up and process antigen. APCs and free antigen are carried in afferent lymphatics to regional lymph nodes. Here APCs display processed antigen to recirculating T lymphocytes, activating antigen-specific cells. Activated T cells proliferate and differentiate into antigen-specific effector cells and leave the lymph node via efferent lymphatics, re-enter the blood stream and migrate to the site of infection.

Pores also render the cell susceptible to osmotic lysis. The action of perforin and granzymes can result in apoptosis or necrosis of the target cell. In addition to killing target cells, NK cells secrete cytokines including ␥-IFN, biasing subsequent adaptive responses towards a cellular immune response, which is the effector mechanism required for recovery from viral infections. 5 Innate Immune Responses II – The Complement System The complement system is part of the innate immune system and includes over 20 functionally linked soluble plasma proteins.

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Concise Clinical Immunology for Health Professionals by Mary Keogan, Eleanor M. Wallace, Paula O'Leary


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