Download e-book for iPad: Cytokines by Anthony R. Mire-Sluis and Robin Thorpe (Eds.)

By Anthony R. Mire-Sluis and Robin Thorpe (Eds.)

ISBN-10: 0124983405

ISBN-13: 9780124983403

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The production of IL-3 is, in contrast to other hemopoietic growth factors, restricted to a few cell types, such as activated T lymphocytes and mast cells, underlying its role in inducible but not constitutive hemopoiesis. Beside its effects on immature myeloid progenitor cells, IL-3 acts on mature end-stage myeloid cells, such as basophils and eosinophils, by priming histamine release and generation of leukotrienes by IgE-dependent and -independent mechanisms, suggesting an essential role in allergic responses.

Et al. (1992). Expression of the interleukin-2 receptor on human fibroblasts and its biological significance. Int. Immunol. 4, 739-746. , et al. (1994). A prospective randomized trial evaluating colloid versus crystalloid resuscitation in the treatment of the vascular leak syndrome associated with interleukin-2 therapy. J. Immunother. 15, 22-28. , Avruch, J. E. (1992). Rapamycin-induced inhibition of the 70-kilodalton $6 protein kinase. Science 257, 973-977. W. A. (1994). Rapid exacerbation of scleroderma in a patient treated with interleukin 2 and lymphokine activated killer cells for renal cell carcinoma.

A. (1996). Rational interleukin 2 therapy for HIV positive individuals: Daily low doses enhance immune function without toxicity. Proc. Natl Acad. Sci. USA 93, 10405-10410. , Kingston, R. J. (1987). Importance of IL-2 receptors in intra-thymic generation of cells expressing T-cell receptors. Nature 329, 160-162. , Efrat, S. and Marsh, S. (1987). Regulation of human interleukin 2 gene expression. In "Lymphokines, Vol. 13, Molecular Cloning and Analysis of Lymphokines", (eds. R. V. Goeddel), pp. 59-72.

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Cytokines by Anthony R. Mire-Sluis and Robin Thorpe (Eds.)

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