By W. R. Hein (auth.), Professor Dr. Jean-Pierre Kraehenbuhl, Professor Dr. Marian R. Neutra (eds.)
Mucosal immunity contains a extensive box of study that incorporates components of epithelial mobilephone and molecular biology, molecular and mobile immunology, microbiology, virology, and vaccinology. This quantity offers brand new and concise discussions of strategies in addition to fresh advances. It presents an outline of the elements of the mucosal immune method, and the elemental technology appropriate to mucosal vaccination. The authors investigate present examine in severe components together with: association of mucosal lymphoid tissue; antigen sampling and presentation in mucosal tissues; mucosalimmune responses and tolerance; immune effectors at mucosal websites; microbial-host interactions at mucosal websites; mucosal vaccines and adjuvants. This multi-disciplinary attempt may be a worthy source for researchers, clinicians and scholars who desire a transparent figuring out of innovations and a advisor to the wide-ranging literature during this very energetic learn area.
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Extra resources for Defense of Mucosal Surfaces: Pathogenesis, Immunity and Vaccines
Histochemistry 99:201-211 Frey A, Lencer WI, Weltzin R, Giannasca KT, Giannasca PI, Neutra MR (1996) Role of the glycocalyx in regulating access of microparticles to apical plasma membranes of intestinal epithelial cells: implications for microbial attachment and oral vaccine targeting. J Exp Med 184:1045-1060 Fujimura Y, Kihara T, Mine H (1992) Membranous cells as a portal ofYersinia pseudotuberculosis entry into rabbit ileum. J Clin Electron Microsc 25:35-45 Gebert A, Hach G (1993) Differential binding of lectins to M cells and enterocytes in the rabbit cecum.
Isolation of Mucosal DCs . Kinetic Studies. . Steady State . . . . Stimulated Migration . . Properties of DCs Isolated from Mucosae Gastrointestinal Tract Respiratory Tract . . . . . . . Peyer's Patches . . . . . . . . Ag Acquisition by Mucosal DCs in Vivo. Mucosal DC and Human Immunodeficiency Virus Role of DCs in Regulation of Mucosal Immune Responses. 41 41 41 41 42 42 43 43 44 44 44 45 46 46 47 48 3 Conclusions and Future Directions . 49 References . . . . . . . .
Ag Acquisition by Mucosal DCs in Vivo. Mucosal DC and Human Immunodeficiency Virus Role of DCs in Regulation of Mucosal Immune Responses. 41 41 41 41 42 42 43 43 44 44 44 45 46 46 47 48 3 Conclusions and Future Directions . 49 References . . . . . . . . . G. M. Liu 1 What Is a Dendritic Cell? 1 Introduction Dendritic cells (DC) represent heterogenous populations of bone marrow-derived cells that have central roles in the initiation and regulation of immune responses (reviewed in STEINMAN 1991).
Defense of Mucosal Surfaces: Pathogenesis, Immunity and Vaccines by W. R. Hein (auth.), Professor Dr. Jean-Pierre Kraehenbuhl, Professor Dr. Marian R. Neutra (eds.)